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hrp0097p1-407 | Adrenals and HPA Axis | ESPE2023

17OHP levels to diagnose Non-Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency (NC-CAH) in children with precocious pubarche

Chagas Nathália , Aragon Davi , Mermejo Livia , de Castro Margaret , Moreira Ayrton , Antonini Sonir

Background: Basal 17OHP levels to indicate an ACTH-stimulation test and post-ACTH 17OHP cut-off levels diagnosing NC-CAH vary among different guidelines.Objective: To establish the performance of basal and post-ACTH 17OHP concentrations for the NC-CAH diagnosis in children with precocious pubarche (PP).Methods: Clinical, biochemical, and molecular analysis from 202 PP patients subm...

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hrp0089p1-p024 | Adrenals and HPA Axis P1 | ESPE2018

Gonadotropin-Dependent Pubertal Disorders are Common in Patients with Virilizing Adrenocortical Tumors in Childhood

Stecchini Monica F , Braid Zilda , More Candy B , Aragon Davi C , Castro Margaret , Moreira Ayrton C , Antonini Sonir R

Background: In pediatric patients with adrenocortical tumors (ACT), morbidity and mortality rates have been extensively evaluated. However, there are almost no data on the late consequences of early exposure to high androgen levels on pubertal development and on final height (FH) in these patients.Objective: To investigate the impact of early exposure to androgen excess on gonadotropin-dependent pubertal development and on final height (...

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ESPE Abstracts

17OHP levels to diagnose Non-Classic Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency (NC-CAH) in children with precocious pubarche

Gonadotropin-Dependent Pubertal Disorders are Common in Patients with Virilizing Adrenocortical Tumors in Childhood

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